Custom Synthetic Intermediates
103962-05-6
Boiling point: 177-179 °C(lit.)
Density: 1.84 g/mL at 25 °C(lit.)
Flash point: 172 °F
Storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Availability: | |
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Product Description
We are a pharmaceutical intermediate manufacturer of 4-(Trifluoromethoxy)iodobenzen.
Its CAS No. is 103962-05-6
Our pharmaceutical intermediates can be used in a variety of APIs.
Product Category | Custom Synthetic Intermediates |
CAS NO | 103962-05-6 |
Product Specifications | Boiling point: 177-179 °C(lit.) Density: 1.84 g/mL at 25 °C(lit.) Flash point: 172 °F Storage temp.: Keep in dark place,Sealed in dry,Room Temperature |
Office Environment
Laboratory
Workshop/Warehouse
Certificate
4-(Trifluoromethoxy)iodobenzen is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
yes , you can have 1 4-(Trifluoromethoxy)iodobenzen sample for starting the business , but it is not free
please contact sale team for detail .
4-(Trifluoromethoxy)iodobenzene (CAS 103962-05-6) is an aromatic compound with the molecular formula C₇H₄F₃IO. It features an iodine substituent and trifluoromethoxy group in para-position on a benzene ring, serving as a versatile building block in synthetic chemistry.
This compound appears as a colorless to pale yellow liquid at room temperature. It has a molecular weight of 291.01 g/mol, boiling point of approximately 210-215°C, and density around 1.9 g/cm³. The compound is soluble in common organic solvents but insoluble in water.
For optimal stability, store in amber glass bottles under inert atmosphere (nitrogen or argon) at temperatures below 25°C. The container should be tightly sealed and protected from light exposure. Handling should occur in a fume hood with standard PPE including nitrile gloves and safety goggles.
This compound is particularly valuable for:
Palladium-catalyzed cross-coupling reactions (Suzuki, Heck, Sonogashira)
Nucleophilic aromatic substitutions
Preparation of liquid crystals and electronic materials
Pharmaceutical intermediate synthesis
The compound may cause skin and eye irritation. Avoid inhalation of vapors and direct contact. In case of exposure, flush affected areas with copious water and seek medical attention if irritation persists. Always review the material safety data sheet before use.
Quality assessment includes:
GC or HPLC analysis (typically ≥97% purity)
Iodine content verification
⊃1;H and ⊃1;⁹F NMR spectroscopy
Refractive index measurement (n20/D ~1.52)
The combination of strong electron-withdrawing trifluoromethoxy group and excellent leaving group (iodine) creates exceptional reactivity in:
Electrophilic aromatic substitutions
Metal-halogen exchange reactions
Radical reactions The iodine atom shows particular utility in transition metal-catalyzed processes.
This specialty chemical is available through fine chemical suppliers in various quantities. Standard packaging includes 1g, 5g, 25g, and 100g options, with custom quantities available for industrial-scale applications. Many suppliers provide technical support for application development.