Custom Synthetic Intermediates
315-31-1
Melting point: 114-116 °C
Boiling point: 258.4±20.0 °C(Predicted)
Density: 1.258±0.06 g/cm3(Predicted)
Storage temp.: Sealed in dry,Room Temperature
Availability: | |
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Product Description
We are a pharmaceutical intermediate manufacturer of 2-Fluoro-3-methylbenzoic acid.
Its CAS No. is 315-31-1
Our pharmaceutical intermediates can be used in a variety of APIs.
Product Category | Custom Synthetic Intermediates |
CAS NO | 315-31-1 |
Product Specifications | Melting point: 114-116 °C Boiling point: 258.4±20.0 °C(Predicted) Density: 1.258±0.06 g/cm3(Predicted) Storage temp.: Sealed in dry,Room Temperature |
Office Environment
Laboratory
Workshop/Warehouse
Certificate
2-Fluoro-3-methylbenzoic acid is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
yes , you can have 1 2-Fluoro-3-methylbenzoic acid sample for starting the business , but it is not free
please contact sale team for detail .
2-Fluoro-3-methylbenzoic acid (CAS 315-31-1) is a fluorinated aromatic carboxylic acid with molecular formula C₈H₇FO₂. This white to off-white crystalline solid features a fluorine atom at the ortho position and a methyl group at the meta position relative to the carboxyl group, making it a valuable intermediate in pharmaceutical and agrochemical synthesis.
The compound typically appears as a white to light beige crystalline powder with a molecular weight of 154.14 g/mol. It has a melting point range of 105-110°C and demonstrates good solubility in polar organic solvents like ethanol and acetone, while being sparingly soluble in water. The material is stable at room temperature under normal storage conditions.
For optimal stability, store in tightly sealed containers at room temperature, protected from excessive moisture and light. While the compound is relatively stable, storage under inert atmosphere (nitrogen or argon) is recommended for long-term preservation. Properly stored material maintains excellent stability for at least 36 months. Keep away from strong oxidizing agents.
This compound serves as a versatile building block in medicinal chemistry, particularly for developing fluorinated pharmaceutical compounds. The carboxyl group enables various derivatization reactions including esterification and amide formation, while the methyl group provides an additional site for functionalization. It's especially useful in designing non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
The compound may cause mild skin and eye irritation. Appropriate personal protective equipment including nitrile gloves and safety goggles should be worn during handling. Work should be conducted in a well-ventilated area. Avoid inhalation of dust and direct contact with skin or eyes. In case of exposure, flush affected areas with water for 15 minutes.
Quality control involves HPLC analysis (typically showing ≥98% purity), melting point determination, and spectroscopic characterization. FTIR confirms the presence of the carboxyl group, while ⊃1;H and ⊃1;⁹F NMR provide structural verification. Elemental analysis may be performed for comprehensive quality assessment when required for pharmaceutical applications.
The strategic positioning of substituents creates unique electronic properties where the fluorine atom influences the acidity of the carboxyl group while the methyl group provides steric and electronic effects that can direct further functionalization. This combination makes the compound particularly useful for structure-activity relationship studies in drug discovery.
This specialty chemical is commercially available through fine chemical suppliers in quantities ranging from grams to kilograms. Many suppliers provide certificates of analysis with each batch and can accommodate custom synthesis requests. Technical support is typically available for specific application questions and scale-up requirements.