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Custom Synthetic Intermediates
825-22-9
Melting point: 171-172°C
Boiling point: 294.4±25.0 °C(Predicted)
Density: 1.430±0.06 g/cm3(Predicted)
Storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Product Description
We are a pharmaceutical intermediate manufacturer of 2-Amino-3-fluorobenzoic acid.
Its CAS No. is 825-22-9
Our pharmaceutical intermediates can be used in a variety of APIs.
| Product Category | Custom Synthetic Intermediates |
| CAS NO | 825-22-9 |
| Product Specifications | Melting point: 171-172°C Boiling point: 294.4±25.0 °C(Predicted) Density: 1.430±0.06 g/cm3(Predicted) Storage temp.: Keep in dark place,Sealed in dry,Room Temperature |
Office Environment
Laboratory
Workshop/Warehouse
Certificate
2-Amino-3-fluorobenzoic acid is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
yes , you can have 1 2-Amino-3-fluorobenzoic acid sample for starting the business , but it is not free
please contact sale team for detail .
2-Amino-3-fluorobenzoic acid (CAS 825-22-9) is a fluorinated aromatic compound with molecular formula C₇H₆FNO₂. This off-white to beige crystalline solid contains both an amino group and carboxylic acid functionality on a fluorine-substituted benzene ring, making it a versatile building block for pharmaceutical and agrochemical synthesis.
The compound typically appears as a light beige to tan crystalline powder with a molecular weight of 155.13 g/mol. It has a melting point range of 185-190°C and demonstrates moderate solubility in polar organic solvents like methanol and DMSO, though limited solubility in water. The material is stable at room temperature but may gradually darken upon prolonged exposure to air and light.
For optimal stability, store in tightly sealed containers protected from light and moisture at room temperature. While relatively stable, the material benefits from storage under inert atmosphere (nitrogen or argon) for long-term preservation. Properly stored, it maintains good stability for at least 24 months. Keep away from strong oxidizing agents.
This bifunctional compound serves as a valuable intermediate in medicinal chemistry, particularly for developing fluorinated pharmaceutical compounds. The amino group enables amide bond formation or diazotization reactions, while the carboxylic acid allows for esterification or coupling reactions. It's especially useful in designing antibacterial agents and CNS drugs.
The compound may cause mild irritation to skin, eyes, and respiratory system. Standard laboratory PPE including gloves and safety goggles is recommended when handling. While not highly toxic, avoid inhalation of dust and direct contact. In case of exposure, flush affected areas with water and consult safety data sheets for specific first aid measures.
Quality control involves multiple analytical techniques including HPLC (typically showing ≥97% purity), melting point determination, and spectroscopic methods. FTIR confirms the presence of both carboxylic acid (1700 cm⁻⊃1;) and amino groups, while ⊃1;H and ⊃1;⁹F NMR provide structural verification. Elemental analysis may also be performed for comprehensive characterization.
The strategic positioning of fluorine adjacent to both amino and carboxyl groups creates interesting electronic properties and reactivity patterns. This arrangement allows for selective functionalization at different positions and enhances the compound's utility in designing bioactive molecules with improved physicochemical properties.
The compound is available through specialty chemical suppliers in quantities ranging from grams to kilograms. Many suppliers provide certificates of analysis with each batch and can accommodate custom synthesis requests. Technical support is typically available for specific application questions and scale-up requirements.
