7697-23-6 2-Fluoro-4-methylbenzoic acid

7697-23-6 2-Fluoro-4-methylbenzoic acid Introduction

We are a pharmaceutical intermediate manufacturer of 2-Fluoro-4-methylbenzoic acid.

Its CAS No. is 7697-23-6

Our pharmaceutical intermediates can be used in a variety of APIs.

7697-23-6 2-Fluoro-4-methylbenzoic acid Specifications

7697-23-6 2-Fluoro-4-methylbenzoic acid Factory display

Office Environment

Laboratory

Workshop/Warehouse

7697-23-6 2-Fluoro-4-methylbenzoic acid Certification

Certificate

7697-23-6 2-Fluoro-4-methylbenzoic acid FAQ

1. Manufacturer or trading company for 7697-23-6 2-Fluoro-4-methylbenzoic acid?

2-Fluoro-4-methylbenzoic acid is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .

2. 7697-23-6 2-Fluoro-4-methylbenzoic acid supplier and factories or wholesale locates in such countries like?

China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.

3. Can I get a sample for trying 7697-23-6 2-Fluoro-4-methylbenzoic acid?

yes , you can have 1 2-Fluoro-4-methylbenzoic acid sample for starting the business , but it is not free

4. What the MOQ of 7697-23-6 2-Fluoro-4-methylbenzoic acid?

please contact sale team for detail .

5. What is 2-Fluoro-4-methylbenzoic acid?

2-Fluoro-4-methylbenzoic acid (CAS 7697-23-6) is a fluorinated aromatic carboxylic acid with molecular formula C₈H₇FO₂. This white to off-white crystalline solid features a fluorine atom at the ortho position and a methyl group at the para position relative to the carboxyl group, serving as a versatile intermediate in pharmaceutical and specialty chemical synthesis.

6. What are the physical properties of this compound?

The compound typically appears as white crystalline flakes or powder with a molecular weight of 154.14 g/mol. It has a melting point range of 120-125°C and demonstrates good solubility in polar organic solvents like methanol and ethyl acetate, while being sparingly soluble in water (approximately 1-5 mg/mL at 25°C). The material is stable at room temperature under normal storage conditions.

7. How should this chemical be stored properly?

For optimal stability, store in tightly sealed containers at room temperature, protected from excessive moisture and light exposure. While the compound is relatively stable, storage under inert atmosphere (nitrogen or argon) is recommended for long-term preservation of high-purity material. Properly stored batches maintain excellent stability for at least 36 months. Keep away from strong bases and oxidizing agents.

8. What are the primary applications in organic synthesis?

This compound serves as a key building block in medicinal chemistry, particularly for developing fluorinated pharmaceutical compounds. The carboxyl group enables various derivatization reactions including conversion to acid chlorides, esters, and amides. It's especially valuable in synthesizing non-steroidal anti-inflammatory drugs (NSAIDs) and liquid crystal materials, where the fluorine-methyl substitution pattern provides optimal electronic and steric properties.

9. What safety precautions should be observed?

The compound may cause mild skin and eye irritation upon contact. Appropriate personal protective equipment including chemical-resistant gloves (nitrile or neoprene) and safety goggles should be worn during handling. While not highly toxic, avoid inhalation of dust and work in a well-ventilated area or fume hood when handling larger quantities. In case of eye contact, flush immediately with plenty of water for at least 15 minutes and seek medical attention if irritation persists.

10. How is purity typically verified?

Quality control involves multiple analytical techniques including HPLC analysis (typically showing ≥98% purity), melting point determination, and comprehensive spectroscopic characterization. FTIR spectroscopy confirms the carboxyl group presence (C=O stretch ~1680 cm⁻⊃1;), while ⊃1;H NMR (showing characteristic aromatic proton patterns) and ⊃1;⁹F NMR provide structural verification. For pharmaceutical applications, additional tests like residual solvent analysis and heavy metal content may be required.

11. What makes this compound chemically valuable?

The strategic 2-fluoro-4-methyl substitution pattern creates unique electronic properties where the fluorine atom influences both the acidity of the carboxyl group and the electron density of the aromatic ring, while the para-methyl group provides steric stabilization. This combination enables selective functionalization at multiple positions, making the compound particularly valuable for structure-activity optimization in drug discovery programs.

12. Where can researchers obtain this material?

This specialty chemical is commercially available through multiple fine chemical suppliers in various packaging options from laboratory-scale (1g, 5g, 25g) to bulk quantities (kg scale). Reputable suppliers typically provide certificates of analysis with each batch and can offer additional technical data including chromatograms and spectral characterization upon request. Custom synthesis and purification services are often available for specific research requirements.