446-32-2 2-Amino-4-fluorobenzoic acid

446-32-2 2-Amino-4-fluorobenzoic acid Introduction

We are a pharmaceutical intermediate manufacturer of 2-Amino-4-fluorobenzoic acid.

Its CAS No. is 446-32-2

Our pharmaceutical intermediates can be used in a variety of APIs.

446-32-2 2-Amino-4-fluorobenzoic acid Specifications

446-32-2 2-Amino-4-fluorobenzoic acid Factory display

Office Environment

Laboratory

Workshop/Warehouse

446-32-2 2-Amino-4-fluorobenzoic acid Certification

Certificate

446-32-2 2-Amino-4-fluorobenzoic acid FAQ

1. Manufacturer or trading company for 446-32-2 2-Amino-4-fluorobenzoic acid?

2-Amino-4-fluorobenzoic acid is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .

2. 446-32-2 2-Amino-4-fluorobenzoic acid supplier and factories or wholesale locates in such countries like?

China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.

3. Can I get a sample for trying 446-32-2 2-Amino-4-fluorobenzoic acid?

yes , you can have 1 2-Amino-4-fluorobenzoic acid sample for starting the business , but it is not free

4. What the MOQ of 446-32-2 2-Amino-4-fluorobenzoic acid?

please contact sale team for detail .

5. What is 2-Amino-4-fluorobenzoic acid?

2-Amino-4-fluorobenzoic acid (CAS 446-32-2) is a fluorinated aromatic compound with molecular formula C₇H₆FNO₂. This off-white to tan crystalline powder contains both an amino group and carboxylic acid functionality on a fluorine-substituted benzene ring, serving as a key intermediate in pharmaceutical and agrochemical synthesis.

6. What are the physical properties?

The compound typically appears as a light tan to beige crystalline solid with a molecular weight of 155.13 g/mol. It has a melting point range of 208-212°C and shows moderate solubility in polar organic solvents like methanol and DMSO, while being poorly soluble in water. The material is stable at room temperature but may gradually darken upon prolonged exposure to air and light.

7. How should this chemical be stored?

For optimal stability, store in tightly sealed containers protected from light and moisture at room temperature. While relatively stable, storage under inert atmosphere (nitrogen or argon) is recommended for long-term preservation. Properly stored material maintains excellent stability for at least 36 months. Keep away from strong oxidizing agents.

8. What are the primary applications?

This bifunctional compound serves as a valuable building block in medicinal chemistry, particularly for developing fluorinated pharmaceutical compounds. The amino group enables various derivatization reactions, while the carboxylic acid allows for esterification or coupling reactions. It's especially useful in designing antibacterial agents and CNS-active compounds.

9. What safety precautions should be observed?

The compound may cause mild skin and eye irritation. Appropriate personal protective equipment including nitrile gloves and safety goggles should be worn during handling. Work should be conducted in a well-ventilated area. Avoid inhalation of dust and direct contact with skin or eyes. In case of exposure, flush affected areas with water.

10. How is purity typically verified?

Quality control involves HPLC analysis (typically showing ≥98% purity), melting point determination, and spectroscopic characterization. FTIR confirms the presence of both carboxylic acid and amino groups, while ⊃1;H and ⊃1;⁹F NMR provide structural verification. Elemental analysis may be performed for comprehensive quality assessment.

11. What makes this compound chemically valuable?

The strategic combination of fluorine substitution with both amino and carboxyl functionalities creates unique electronic properties and reactivity patterns. This arrangement allows for selective functionalization and enhances the compound's utility in designing bioactive molecules with improved physicochemical properties and metabolic stability.

12. Where can researchers obtain this material?

This specialty chemical is commercially available through fine chemical suppliers in quantities ranging from grams to kilograms. Many suppliers provide certificates of analysis with each batch and can accommodate custom synthesis requests. Technical support is typically available for specific application questions and scale-up requirements.