Views: 0 Author: Site Editor Publish Time: 2025-07-28 Origin: Site
CAS No. 106261-64-7, known as Tenofovir disoproxil, is a pivotal pharmaceutical intermediate used in the manufacture of Tenofovir disoproxil fumarate (TDF), a widely prescribed antiviral drug for HIV/AIDS and chronic hepatitis B treatment.
This intermediate is essential for creating the orally bioavailable prodrug form of Tenofovir, improving drug absorption and efficacy.
Enables the synthesis of Tenofovir disoproxil fumarate, enhancing pharmacokinetics and patient compliance.
TDF is a WHO-recommended drug used extensively in global treatment programs.
Manufacturers must ensure compliance with FDA, EMA, and WHO GMP guidelines.
Intermediate supply is crucial to both originator and generic pharmaceutical companies.
Global health initiatives depend on reliable, well-documented intermediates.
Location: Foster City, California, USA
Overview: Original innovator of Tenofovir disoproxil fumarate; oversees global licensing and quality standards.
Specialty: High compliance and proprietary processes.
Location: Barcelona, Spain
Overview: Specializes in antiviral intermediates including Tenofovir prodrug precursors, supplying multiple global generic producers.
Specialty: GMP-certified scalable manufacturing.
Location: Changzhou City, Jiangsu Province, China
Overview: Eastfine provides high-quality CAS 106261-64-7 with strict stereochemical control and regulatory documentation for export worldwide.
Specialty: Cost-effective and consistent supply for antiviral APIs.
Location: Hyderabad, India
Overview: Offers CDMO services and large-scale production of nucleoside prodrug intermediates.
Specialty: Process development and regulatory expertise.
Location: Milan, Italy
Overview: European-based manufacturer with FDA and EMA audited facilities for antiviral intermediates.
Specialty: High-purity production and supply chain reliability.
Location: Mumbai, India
Overview: Manufactures TDF intermediates and APIs, supporting global public health antiviral programs.
Specialty: WHO prequalification and affordable antiviral drug supply.
Location: Bubendorf, Switzerland
Overview: Provides custom and commercial GMP manufacturing of antiviral intermediates including Tenofovir disoproxil.
Specialty: Advanced analytical and regulatory support.
Location: Montreal, Canada
Overview: Supplies antiviral intermediates with emphasis on North American and global market compliance.
Specialty: Regulatory documentation and quality systems.
Location: Maharashtra, India
Overview: Manufactures a range of pharmaceutical intermediates, including nucleotide prodrugs for antiviral APIs.
Specialty: Industrial scale GMP production.
Location: Gujarat, India
Overview: Provides pharmaceutical intermediates for antivirals with robust quality management systems.
Specialty: Reliable supply and process optimization.
Growing global treatment programs maintain strong need for Tenofovir disoproxil intermediates.
Stringent impurity and stability criteria push manufacturers toward continuous process improvements.
Pharmaceutical companies increasingly rely on specialized CDMOs for intermediate production.
Efforts to reduce environmental impact are shaping synthetic methods for phosphonate prodrugs.
Buyers favor diversified sourcing from India, Europe, and trusted Chinese suppliers like Eastfine.
CAS No. 106261-64-7 is a cornerstone intermediate enabling the production of Tenofovir disoproxil fumarate, a key antiviral medicine for HIV and hepatitis B. With trusted suppliers such as Eastfine, Farmhispania, Sai Life Sciences, and Olon, the global supply chain remains resilient and high quality.
As public health programs expand access to antiviral drugs worldwide, reliable production and supply of this intermediate are critical to sustaining treatment efforts.
简体中文
