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Custom Synthetic Intermediates
93249-44-6
Boiling point: 89 °C15 mm Hg(lit.)
Density: 1.129 g/mL at 25 °C(lit.)
Flash point: 178 °F
Storage temp.: Inert atmosphere,2-8°C
Product Description
We are a pharmaceutical intermediate manufacturer of 2-Fluoro-5-methylbenzaldehyde.
Its CAS No. is 93249-44-6
Our pharmaceutical intermediates can be used in a variety of APIs.
| Product Category | Custom Synthetic Intermediates |
| CAS NO | 93249-44-6 |
| Product Specifications | Boiling point: 89 °C15 mm Hg(lit.) Density: 1.129 g/mL at 25 °C(lit.) Flash point: 178 °F Storage temp.: Inert atmosphere,2-8°C |
Office Environment
Laboratory
Workshop/Warehouse
Certificate
2-Fluoro-5-methylbenzaldehyde is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
yes , you can have 1 2-Fluoro-5-methylbenzaldehyde sample for starting the business , but it is not free
please contact sale team for detail .
2-Fluoro-5-methylbenzaldehyde (CAS 93249-44-6) is an aromatic aldehyde compound with the molecular formula C₈H₇FO. This colorless to pale yellow liquid features a fluorine atom at the ortho position and a methyl group at the meta position relative to the formyl functional group, making it a valuable intermediate in pharmaceutical and specialty chemical synthesis.
The compound typically appears as a clear, slightly yellow liquid with a characteristic aromatic odor. It has a molecular weight of 138.14 g/mol and boils at approximately 85-90°C at 12 mmHg. The density is about 1.13 g/cm³ at 25°C, and it demonstrates good solubility in common organic solvents like ethanol, ether, and dichloromethane while being nearly insoluble in water.
For optimal stability, store in tightly sealed amber glass containers under inert atmosphere (nitrogen or argon) at temperatures between 2-8°C. The material should be protected from light exposure and moisture. Under proper storage conditions, it maintains excellent stability for at least 18 months. Keep separate from strong oxidizing agents and bases.
This compound serves as a versatile building block in organic synthesis, particularly for developing fluorinated pharmaceutical compounds. The aldehyde group participates in various condensation reactions, while the fluorine substituent enhances metabolic stability in drug candidates. It's especially valuable in synthesizing kinase inhibitors and other bioactive molecules.
The material may cause skin and eye irritation. Appropriate personal protective equipment including nitrile gloves and chemical safety goggles should be worn during handling. All work should be conducted in a well-ventilated area or fume hood. Avoid inhalation of vapors and direct contact with skin or clothing. In case of exposure, flush affected areas with copious amounts of water.
Quality control includes gas chromatography analysis (typically showing ≥97% purity), refractive index measurement (n20/D ~1.51), and spectroscopic characterization. FTIR confirms the aldehyde carbonyl stretch (~1690 cm⁻⊃1;), while ⊃1;H NMR provides structural verification. Mass spectrometry may be used for molecular weight confirmation in critical applications.
The strategic positioning of fluorine and methyl groups creates unique electronic effects on the aromatic ring. The fluorine atom activates the aldehyde group toward nucleophilic attack while improving the metabolic stability of derivatives. The methyl group offers additional sites for further functionalization, enhancing the compound's versatility in multi-step syntheses.
This specialty chemical is commercially available through fine chemical suppliers in quantities ranging from grams to kilograms. Many suppliers provide certificates of analysis with each batch and offer custom synthesis services for specific research or production requirements. Technical support is typically available for application development and scale-up questions.
