77771-02-9 3-Bromo-4-fluorobenzaldehyde

77771-02-9 3-Bromo-4-fluorobenzaldehyde Introduction

We are a pharmaceutical intermediate manufacturer of 3-Bromo-4-fluorobenzaldehyde.

Its CAS No. is 77771-02-9

Our pharmaceutical intermediates can be used in a variety of APIs.

77771-02-9 3-Bromo-4-fluorobenzaldehyde Specifications

77771-02-9 3-Bromo-4-fluorobenzaldehyde Factory display

Office Environment

Laboratory

Workshop/Warehouse

77771-02-9 3-Bromo-4-fluorobenzaldehyde Certification

Certificate

77771-02-9 3-Bromo-4-fluorobenzaldehyde FAQ

1. Manufacturer or trading company for 77771-02-9 3-Bromo-4-fluorobenzaldehyde?

3-Bromo-4-fluorobenzaldehyde is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .

2. 77771-02-9 3-Bromo-4-fluorobenzaldehyde supplier and factories or wholesale locates in such countries like?

China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.

3. Can I get a sample for trying 77771-02-9 3-Bromo-4-fluorobenzaldehyde?

yes , you can have 1 3-Bromo-4-fluorobenzaldehyde sample for starting the business , but it is not free

4. What the MOQ of 77771-02-9 3-Bromo-4-fluorobenzaldehyde?

please contact sale team for detail .

5. What is 2-Chloro-4-(trifluoromethyl)pyrimidine?

2-Chloro-4-(trifluoromethyl)pyrimidine (CAS 77771-02-9) is a fluorinated heterocyclic compound with molecular formula C₅H₂ClF₃N₂. This pyrimidine derivative features a reactive chlorine atom at the 2-position and an electron-withdrawing trifluoromethyl group at the 4-position, serving as a key building block in pharmaceutical and agrochemical synthesis.

6. What are the physical properties of this compound?

The compound typically appears as a colorless to pale yellow liquid with a molecular weight of 182.53 g/mol. It has a boiling point of approximately 72-75°C at 15 mmHg and shows good solubility in common organic solvents including dichloromethane, ethanol, and ether. The density is about 1.5 g/cm³ at 25°C.

7. How should this chemical be properly stored?

For optimal stability, store in tightly sealed amber glass bottles under inert atmosphere (nitrogen or argon) at temperatures between 2-8°C. The material is moisture-sensitive and should be protected from light exposure. Properly stored, it maintains stability for at least 12 months.

8. What are the main synthetic applications?

This versatile intermediate is particularly valuable for constructing pyrimidine-containing pharmaceuticals, especially antiviral and anticancer agents. The chlorine atom undergoes facile nucleophilic substitution reactions, allowing introduction of various functional groups. The trifluoromethyl group enhances metabolic stability in resulting compounds.

9. What safety precautions should be observed?

The compound may cause skin and eye irritation. Appropriate PPE including nitrile gloves, chemical goggles, and lab coat should be worn. All handling should occur in a fume hood. Avoid contact with moisture as it may decompose to release hydrogen chloride. In case of exposure, flush affected areas with water.

10. How is the purity typically verified?

Quality assessment includes GC analysis (typically ≥98% purity), ⊃1;H and ⊃1;⁹F NMR spectroscopy, and refractive index measurement (n20/D ~1.45). Mass spectrometry provides molecular weight confirmation. For critical applications, residual solvent analysis may be performed.

11. What makes this compound chemically unique?

The combination of a reactive chlorine substituent and strong electron-withdrawing trifluoromethyl group on the pyrimidine ring creates exceptional versatility. The chlorine shows high selectivity for nucleophilic displacement, while the trifluoromethyl group enhances the electrophilicity of adjacent positions.

12. Where can researchers obtain this material?

This specialty chemical is available through fine chemical suppliers in quantities ranging from grams to kilograms. Many suppliers provide technical data sheets with detailed specifications. Custom synthesis and purification services are often available for specific research needs.