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Custom Synthetic Intermediates
63082-45-1
Boiling point: 87 14mm
Density: 1.144 g/mL at 25 °C
Storage temp.: Inert atmosphere,2-8°C
Product Description
We are a pharmaceutical intermediate manufacturer of 4-Fluoro-2-methylbenzaldehyde.
Its CAS No. is 63082-45-1
Our pharmaceutical intermediates can be used in a variety of APIs.
| Product Category | Custom Synthetic Intermediates |
| CAS NO | 63082-45-1 |
| Product Specifications | Boiling point: 87 14mm Density: 1.144 g/mL at 25 °C Storage temp.: Inert atmosphere,2-8°C |
Office Environment
Laboratory
Workshop/Warehouse
Certificate
4-Fluoro-2-methylbenzaldehyde is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
yes , you can have 1 4-Fluoro-2-methylbenzaldehyde sample for starting the business , but it is not free
please contact sale team for detail .
4-Fluoro-2-methylbenzaldehyde (CAS 63082-45-1) is a fluorinated aromatic compound with the molecular formula C₈H₇FO. This pale yellow to colorless liquid features a fluorine atom at the para position and a methyl group at the ortho position relative to the formyl group, serving as an important intermediate in pharmaceutical and agrochemical synthesis.
The compound typically appears as a clear, colorless to slightly yellow liquid with a characteristic aromatic odor. It has a molecular weight of 138.14 g/mol and boils at approximately 95-100°C at 15 mmHg. The density is about 1.12 g/cm³ at 25°C, and it shows excellent solubility in common organic solvents including ethanol, ether, and dichloromethane.
For maximum stability, store in tightly sealed amber glass containers under inert atmosphere (nitrogen or argon) at temperatures between 2-8°C. The material should be protected from light exposure and moisture. When stored under these conditions, it maintains good stability for at least 24 months. Keep away from strong oxidizing agents and bases.
This versatile intermediate is primarily used in the synthesis of fluorinated pharmaceutical compounds, particularly in the development of active ingredients for central nervous system drugs and anti-inflammatory agents. The aldehyde group enables various condensation reactions, while the fluorine substituent enhances the metabolic stability of resulting compounds.
The compound may cause mild skin and eye irritation. Appropriate personal protective equipment including nitrile gloves and chemical safety goggles should be worn during handling. All work should be conducted in a well-ventilated area or fume hood. Avoid inhalation of vapors and direct contact with skin. In case of exposure, flush affected areas with plenty of water.
Quality control involves gas chromatography analysis (typically showing ≥98% purity), refractive index measurement (n20/D ~1.50), and spectroscopic characterization. FTIR spectroscopy confirms the presence of the aldehyde group, while ⊃1;H NMR analysis provides structural verification. Mass spectrometry may be used for molecular weight confirmation.
The strategic combination of fluorine and methyl substituents creates unique electronic properties in the aromatic system. The fluorine atom enhances the reactivity of the aldehyde group while improving the metabolic stability of derivatives. The methyl group provides an additional site for further functionalization, making this compound particularly useful in multi-step syntheses.
This specialty chemical is commercially available through fine chemical suppliers in quantities ranging from grams to kilograms. Many suppliers provide certificates of analysis with each batch and can accommodate custom synthesis requests. Technical support is typically available for specific application questions and scale-up requirements.
