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749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide

We are a pharmaceutical intermediate manufacturer of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide. Its CAS No. is 749927-69-3. Our pharmaceutical intermediates can be used in a variety of APIs such as Articaine, Pyrantel, Bicalutamide, Enzalutamide, etc.
  • Enzalutamide

  • 749927-69-3

  • White to Off-White Solid
    Melting point: 125.0 to 129.0 °C
    Boiling point: 284.8±30.0 °C(Predicted)
    Density: 1.545±0.06 g/cm3(Predicted)
    Storage temp.: Sealed in dry,Room Temperature

Availability:
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Product Description

749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide Introduction


We are a pharmaceutical intermediate manufacturer of 4-Bromo-2-fluoro-N-methylbenzamide.

Its CAS No. is 749927-69-3.

4-Bromo-2-fluoro-N-methylbenzamide is an organic compound that belongs to the class of halogenated amides. It is characterized by a benzamide structure with a bromine atom at the para position (4), a fluorine atom at the meta position (2), and a methyl group attached to the nitrogen of the amide group (N-methyl). The compound has the chemical formula C7H6BrFNO.

Our pharmaceutical intermediates can be used in a variety of APIs such as Articaine, Pyrantel, Bicalutamide, Enzalutamide, etc.


749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide Specifications


Product Category

Enzalutamide

CAS NO

749927-69-3

Product Specifications

White to Off-White Solid

Melting point: 125.0 to 129.0 °C

Boiling point: 284.8±30.0 °C(Predicted)

Density: 1.545±0.06 g/cm3(Predicted)

Storage temp.: Sealed in dry,Room Temperature


749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide PDF


749927-69-3 4-BROMO-2-FLUORO-N-METHYLBENZAMIDE.pdf



749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide Factory display


Office Environment

749927-69-3

Laboratory

Enzalutamide Pharmaceutical intermediates

Workshop/Warehouse

749927-69-3


749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide Certification


Certificate

4-Bromo-2-fluoro-N-methylbenzamide


749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide FAQ


1. Manufacturer or trading company for 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

4-Bromo-2-fluoro-N-methylbenzamide is produced by EASTFINE , and we are in charge of  overseas selling . Not just trading company .


2. 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide supplier and factories or wholesale locates in such countries like?

China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.


3. Can I get a sample for trying 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

Yes , you can have 4-Bromo-2-fluoro-N-methylbenzamide sample for starting the business , but it is not free


4. What the MOQ of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

Please contact our sales team for more details.


5. What is 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

4-Bromo-2-fluoro-N-methylbenzamide is an organic molecule with the formula C7H6BrFNO. It consists of a benzamide group, a bromine atom at the para position (4), a fluorine atom at the meta position (2), and an N-methyl group attached to the nitrogen of the amide.


6. What are the key features of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

· Benzamide Core: The amide group (-CONH2) gives the molecule versatile reactivity, particularly in nucleophilic substitution and hydrolysis reactions.

· Halogen Substituents: The bromine and fluorine atoms are electron-withdrawing and influence the reactivity of the compound, making it suitable for electrophilic aromatic substitution.

· N-Methyl Group: The N-methyl group enhances the basicity of the nitrogen and modifies the compound’s solubility and reactivity.


7. What is the primary use of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

4-Bromo-2-fluoro-N-methylbenzamide is primarily used as an intermediate in organic synthesis. It is useful in the development of pharmaceuticals, biologically active compounds, and materials science, where the halogenated aromatic structure plays a key role in the chemical reactivity and biological activity of the final product.


8. How is 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide synthesized?

This compound can be synthesized by the following general method:

· Halogenation: A methylbenzamide precursor undergoes halogenation to introduce the bromine and fluorine atoms at the desired positions on the aromatic ring.

· The methylation of the nitrogen atom can be achieved using methylating agents such as methyl iodide (CH3I) in the presence of a base, leading to the formation of the N-methyl derivative.


9. What are the physical properties of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

· Appearance: The compound is generally a solid at room temperature, often white to light yellow.

· Melting Point: The melting point of 4-bromo-2-fluoro-N-methylbenzamide is approximately 135–140°C.

· Solubility: It is likely to be insoluble in water but may dissolve in polar organic solvents such as acetone, methanol, and dimethyl sulfoxide (DMSO).


10. Is 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide toxic?

· As with many organic compounds, especially those with halogen atoms, 4-bromo-2-fluoro-N-methylbenzamide should be handled with care. It may cause irritation to the skin, eyes, and respiratory system.

· Always use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat, and work in a well-ventilated area.


11. How do the halogen atoms (Bromine and Fluorine) influence the properties of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

· Bromine at the para position is an electron-withdrawing group that increases the electrophilicity of the aromatic ring, making the compound more reactive in electrophilic aromatic substitution.

· Fluorine at the meta position also acts as an electron-withdrawing group, but due to its smaller size, it affects the electronic properties of the molecule in a more subtle way, increasing the stability and lipophilicity of the compound.


12. What are the potential applications of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide in pharmaceuticals?

The compound can be used as a precursor in the synthesis of bioactive molecules, especially those with antimicrobial, anticancer, or anti-inflammatory properties. The halogen atoms (bromine and fluorine) may contribute to the compound's biological activity, lipophilicity, and ability to interact with biological targets.


13. How stable is 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

4-Bromo-2-fluoro-N-methylbenzamide is stable under standard conditions. However, like most organic compounds, it should be stored in a cool, dry place away from moisture and direct sunlight. Ensure that the compound is kept in airtight containers to prevent degradation or contamination.


14. What is the environmental impact of 749927-69-3 4-Bromo-2-fluoro-N-methylbenzamide?

Halogenated compounds like 4-bromo-2-fluoro-N-methylbenzamide may be persistent in the environment, especially in water or soil. It is important to dispose of this compound according to environmental regulations to avoid contamination. Proper disposal methods, such as using designated waste containers and following institutional guidelines, should be followed to minimize its environmental impact.


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