English
Multi-use Raw Materials
4637-24-5
White to off-white solid
Melting point: -85°C
Boiling point: 102-103 °C/720 mmHg (lit.)
Density: 0.897 g/mL at 25 °C (lit.)
Storage temp.: Store below +30°C
Product Description
| Product Category | Multi-use Raw Materials |
| CAS NO | 4637-24-5 |
| Product Specifications | White to off-white solid Melting point: -85°C Boiling point: 102-103 °C/720 mmHg (lit.) Density: 0.897 g/mL at 25 °C (lit.) Storage temp.: Store below +30°C |
4637-24-5 N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL.pdf
N,N-Dimethylformamide dimethyl acetal is produced by EASTFINE , and we are in charge of overseas selling . Not just trading company .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
Yes , you can have N,N-Dimethylformamide dimethyl acetal sample for starting the business , but it is not free
Please contact our sales team for more details.
N,N-Dimethylformamide dimethyl acetal (DMF-DMA) is a chemical compound used primarily in organic synthesis. It is a derivative of N,N-dimethylformamide (DMF), where the hydrogen atom in the formamide group is replaced by a methyl group. This compound is often used as a reagent or intermediate in the protection of functional groups or reactions involving amines.
DMF-DMA is mainly used as a protecting group for amines. It is employed to prevent unwanted reactions of amines with other reactive species during chemical syntheses, particularly those involving carbonyl compounds. It is also used in reactions to synthesize imines and similar derivatives.
DMF-DMA reacts with aldehydes or ketones to form acetals, which effectively protect the carbonyl group from undergoing unwanted reactions during a multi-step synthesis process. The acetal group can later be removed under acidic or basic conditions, restoring the original functional group.
· Appearance: Colorless liquid.
· Boiling Point: Around 135–140°C.
· Density: Approximately 0.97 g/cm³.
· Solubility: Soluble in water, alcohols, and various organic solvents.
Like many chemicals, DMF-DMA should be handled with caution. It is advisable to avoid direct inhalation or skin contact, and appropriate personal protective equipment (PPE) such as gloves and goggles should be worn when working with it. Additionally, it should be stored in a cool, dry, and well-ventilated area away from incompatible materials.
While DMF-DMA is versatile, it is specifically useful in reactions that involve protecting amines or other sensitive functional groups. It may not be appropriate for every organic reaction, and its suitability depends on the nature of the reactants and the desired outcome.
DMF-DMA is typically synthesized by reacting N,N-dimethylformamide (DMF) with methyl alcohol (methanol). The reaction replaces the hydrogen atom of the formamide group with a methyl group, forming the dimethyl acetal derivative.
Yes, DMF-DMA can be used in combination with other reagents in organic synthesis. It is often employed alongside acids, bases, and other reagents that aid in the formation or cleavage of protective groups.
The acetal group introduced by DMF-DMA can be removed under acidic or basic conditions, typically by hydrolysis, which results in the regeneration of the original functional group, such as an aldehyde or ketone.
As with many chemical reagents, it is important to handle DMF-DMA responsibly to avoid environmental contamination. Proper disposal of waste materials and following local regulations regarding chemical handling and disposal are crucial.
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