Building Block
872-53-7
Clear colorless to light yellow liquid
Boiling point: 140-141 °C (lit.)
Density: 0.919 g/mL at 25 °C (lit.)
Storage temp.: 2-8°C
Availability: | |
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Product Description
Product Category | Building Block |
CAS NO | 872-53-7 |
Product Specifications | Clear colorless to light yellow liquid Boiling point: 140-141 °C (lit.) Density: 0.919 g/mL at 25 °C (lit.) Storage temp.: 2-8°C |
872-53-7 CYCLOPENTANECARBALDEHYDE.pdf
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Cyclopentanecarbaldehyde is an organic compound with the molecular formula C5H8O. It consists of a cyclopentane ring (a five-membered carbon ring) attached to an aldehyde group (-CHO), which is a highly reactive functional group consisting of a carbonyl group (C=O) bonded to a hydrogen atom.
Cyclopentanecarbaldehyde is used in several applications, such as:
· Organic synthesis: It serves as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and materials.
· Flavor and fragrance industry: Aldehydes like cyclopentanecarbaldehyde are used to impart specific aromas or flavors to products.
· As a building block: It can be used to synthesize other cyclopentane derivatives, which may have industrial or bioactive uses.
Cyclopentanecarbaldehyde can be synthesized through various methods, including:
· Oxidation: A common method involves the oxidation of cyclopentene or cyclopentanol to introduce the aldehyde group.
· Hydroformylation: This process involves adding carbon monoxide (CO) and hydrogen (H2) to an alkene, which can result in the formation of aldehydes, including cyclopentanecarbaldehyde.
· Other synthetic routes: Cyclopentanecarbaldehyde may also be obtained via selective functionalization of cyclopentane derivatives in the presence of specific reagents.
· Appearance: Cyclopentanecarbaldehyde is typically a colorless to pale yellow liquid.
· Boiling Point: The boiling point is around 162-164°C (323-327°F).
· Solubility: It is soluble in many organic solvents such as ethanol, ether, and acetone but is relatively insoluble in water due to the non-polar nature of the cyclopentane ring.
As an aldehyde, cyclopentanecarbaldehyde can undergo several key reactions, including:
· Nucleophilic addition: The carbonyl group in the aldehyde is reactive and can undergo nucleophilic addition reactions with nucleophiles like amines, alcohols, or hydrides.
· Reduction: Cyclopentanecarbaldehyde can be reduced to cyclopentanol (a secondary alcohol) using reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4).
· Condensation: The aldehyde group can react with other compounds in condensation reactions, such as aldol condensation.
· Oxidation: Under harsh conditions, cyclopentanecarbaldehyde can be oxidized to cyclopentanecarboxylic acid (a carboxylic acid).
Cyclopentanecarbaldehyde can be moderately toxic and may cause irritation to the skin, eyes, and respiratory tract upon contact or inhalation. It is important to handle the compound with care and use appropriate safety precautions, including wearing gloves, goggles, and working in a well-ventilated area or fume hood.
Yes, cyclopentanecarbaldehyde can be an intermediate in the synthesis of pharmaceuticals and biologically active compounds. Its aldehyde group makes it a reactive building block for various organic transformations, which can be applied to create pharmaceutical agents.
The aldehyde group is highly reactive due to the presence of the carbonyl group (C=O), which is electrophilic and susceptible to nucleophilic attack. This reactivity allows cyclopentanecarbaldehyde to participate in various reactions, such as nucleophilic addition, condensation, and reduction, making it versatile in organic synthesis.
· Protective Equipment: Always wear gloves, safety goggles, and a lab coat when handling cyclopentanecarbaldehyde to avoid skin and eye contact.
· Ventilation: Use a fume hood or ensure good ventilation to avoid inhalation of vapors.
· Storage: Store in a cool, dry place, away from sources of heat or open flames, as aldehydes can be flammable.
· Handling: Avoid prolonged exposure or direct contact, and take appropriate steps if exposure occurs.
Cyclopentanecarbaldehyde is a volatile organic compound (VOC) and may contribute to air pollution if released in large quantities. It is important to handle and dispose of it properly to minimize environmental impact. In the laboratory or industrial setting, using proper containment and disposal procedures is crucial to prevent contamination.