Apalutamide
1191-95-3
Clear colorless to slightly yellow liquid
Melting point: -50.9 °C
Boiling point: 99 °C (lit.)
Density: 0.938 g/mL at 25 °C (lit.)
Storage temp.: 2-8°C
Availability: | |
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Product Description
Product Category | Apalutamide |
CAS NO | 1191-95-3 |
Product Specifications | Clear colorless to slightly yellow liquid Melting point: -50.9 °C Boiling point: 99 °C (lit.) Density: 0.938 g/mL at 25 °C (lit.) Storage temp.: 2-8°C |
Cyclobutanone is produced by EASTFINE , and we are in charge of overseas selling . Not just trading company .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
Yes , you can have Cyclobutanone sample for starting the business , but it is not free
Please contact our sales team for more details.
Cyclobutanone is an organic compound consisting of a cyclobutane ring (a four-membered carbon ring) with a carbonyl group (C=O) attached to one of the carbons in the ring. It has the chemical formula C4H6O and is categorized as a ketone.
· Cyclobutane Ring: Cyclobutanone has a strained four-membered ring, which can contribute to reactivity in chemical reactions.
· Carbonyl Group: The carbonyl group (C=O) is attached to one of the carbons in the cyclobutane ring. This functional group imparts polarity and makes cyclobutanone reactive in nucleophilic addition reactions.
Cyclobutanone is typically synthesized via several methods:
· Cyclization of β-keto esters: One common approach involves the intramolecular cyclization of β-keto esters, where a reactive intermediate undergoes ring closure.
· Photochemical or thermal methods: Cyclobutanone can also be synthesized under specific conditions, such as photochemical or thermal decomposition of precursors like cyclobutyl hydroperoxide.
Cyclobutanone is primarily used as an intermediate in organic synthesis. It can be involved in the creation of more complex organic molecules, including those used in:
· Pharmaceuticals: Cyclobutanone is sometimes used as a starting material for the synthesis of bioactive molecules.
· Polymer Chemistry: It can be used in the preparation of polymers and other functionalized organic materials.
· Chemical Reactions: Due to the strained nature of its ring, cyclobutanone is useful in ring-opening reactions and other synthetic transformations in organic chemistry.
· Appearance: Cyclobutanone is typically a colorless liquid at room temperature.
· Boiling Point: It has a boiling point around 79°C.
· Melting Point: The melting point of cyclobutanone is about 48°C.
· Solubility: It is soluble in most organic solvents (like ether, chloroform, and acetone) but is sparingly soluble in water.
Cyclobutanone is a relatively low-toxicity compound, but as with any chemical, it should be handled with care. It can cause irritation to the skin, eyes, and respiratory system if inhaled or in contact with skin. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when handling it, and it should be used in well-ventilated areas.
The four-membered cyclobutane ring creates ring strain, which makes the molecule more reactive than a non-cyclic ketone. This strain facilitates nucleophilic attack on the carbonyl group and promotes various organic reactions, such as ring-opening reactions and other electrophilic substitution processes.
· Flammability: Like many organic solvents, cyclobutanone is flammable, and precautions should be taken to avoid open flames or sparks in areas where it is used.
· Health Hazards: Prolonged or repeated exposure may cause irritation, and inhaling the vapors can be harmful. Inhalation, skin contact, or ingestion should be avoided.
Cyclobutanone is relatively stable under normal conditions. However, due to the strained ring structure, it can undergo ring-opening reactions under certain conditions, especially when exposed to nucleophiles or other reactive species. It should be stored in airtight containers to protect it from moisture and air.
Yes, cyclobutanone can undergo nucleophilic addition reactions at the carbonyl group, as the strained ring increases the electrophilicity of the carbonyl carbon. This reactivity is commonly utilized in synthetic organic chemistry for constructing more complex molecules.