Articaine
85006-31-1
White to beige crystalline powder
Melting point 83-87℃
Loss on drying ≤0.5%
Residue on ignition ≤0.5%
Total impurities detected by TLC ≤1.0%
Content 98.0%-102.0%
Availability: | |
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Product Description
We are a pharmaceutical intermediate manufacturer of Methyl 3-amino-4-methylthiophene-2-carboxylate.
Its CAS No. is 85006-31-1
Our pharmaceutical intermediates can be used in a variety of APIs such as Articaine, Pyrantel, Bicalutamide, etc.
Product Category | Articaine |
CAS NO | 85006-31-1 |
Product Specifications | White to beige crystalline powder Melting point 83-87℃ Loss on drying ≤0.5% Residue on ignition ≤0.5% Total impurities detected by TLC ≤1.0% Content 98.0%-102.0% |
85006-31-1 METHYL 3-AMINO-4-METHYLTHIOPHENE-2-CARBOXYLATE.pdf
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Methyl 3-amino-4-methylthiophene-2-carboxylate is produced by EASTFINE , and we are in charge of overseas selling . Not just trading compamy .
China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.
yes , you can have 1 Methyl 3-amino-4-methylthiophene-2-carboxylate sample for starting the business , but it is not free
please contact sale team for detail .
Pharmaceutical Research: The thiophene ring is a well-known scaffold in medicinal chemistry. Its electron-rich properties and the ability to modify the molecule's functionality via the amino and ester groups can make this compound a potential precursor in the design of bioactive molecules, particularly for targeting enzymes or receptors.
Polymer Chemistry: Methyl 3-amino-4-methylthiophene-2-carboxylate could potentially serve as a monomer in the synthesis of polymers or copolymers. Thiophene derivatives are widely used in the production of conductive polymers, which can be used in electronic devices like organic semiconductors.
Materials Science: Due to its thiophene structure, this compound might find applications in organic electronics, such as organic light-emitting diodes (OLEDs) or organic photovoltaics (OPVs), where thiophene derivatives often play a key role in the transport of charge carriers.
The thiophene ring is an important feature that imparts several key properties to the compound:
Electron-Rich Nature: The sulfur atom in the thiophene ring has a lone pair of electrons, making the ring electron-rich and reactive. This can influence the compound's ability to participate in electrophilic substitution reactions, which are typical for thiophene derivatives.
The amino group (-NH₂) is a nucleophilic functional group that can participate in a variety of reactions, including:
Amination reactions: The amino group can react with electrophilic reagents to introduce other functional groups or form new bonds.
Hydrogen bonding: The amino group can form hydrogen bonds with other molecules, which may influence the solubility and physical properties of the compound, especially in biological or aqueous environments.
Basicity: The amino group is basic and can accept protons under acidic conditions, which can affect the compound's ionization and reactivity.
Methyl 3-amino-4-methylthiophene-2-carboxylate can be synthesized through several approaches, generally starting with commercially available thiophene derivatives or precursors:
Introduction of the amino group: The amino group can be introduced by nitration followed by reduction or via direct amination of a thiophene derivative.
Methyl ester formation: The ester functionality can be introduced via esterification of 3-amino-4-methylthiophene-2-carboxylic acid with methanol and an acid catalyst or by using methyl iodide in the presence of a base (e.g., potassium carbonate).
Optimizing substitution pattern: The positions of the amino, methyl, and ester groups on the thiophene ring can be controlled through the appropriate synthetic routes, ensuring the desired regioselectivity.
Toxicity: As with many organic compounds, this compound may be toxic if ingested, inhaled, or absorbed through the skin. Always wear personal protective equipment (PPE), including gloves, goggles, and a lab coat.
Reactivity: The amino group and the ester group are reactive, and care should be taken when handling the compound, particularly when working with strong acids or bases, as these could cause hydrolysis or other unwanted reactions.
Flammability: Like many organic compounds, Methyl 3-amino-4-methylthiophene-2-carboxylate may be flammable, so it should be kept away from open flames or heat sources.
Store in a cool, dry, well-ventilated area away from heat or open flames.
Keep in airtight containers to prevent moisture absorption, which could potentially hydrolyze the ester group.
Protect from direct sunlight, as exposure to UV light might lead to degradation or unwanted chemical reactions.