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654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile

We are a pharmaceutical intermediate manufacturer of 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile. Its CAS No. is 654-70-6. Our pharmaceutical intermediates can be used in a variety of APIs.
  • Pharmaceutical intermediates

  • 654-70-6

  • White to off-white powder
    Melting point: 141-145 °C(lit.)
    Boiling point: 294.5±40.0 °C(Predicted)
    Density: 1.37±0.1 g/cm3(Predicted)
    Storage temp.: Keep in dark place,Sealed in dry,Room Temperature

Availability:
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Product Description

654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile Introduction


We are a pharmaceutical intermediate manufacturer of 4-Amino-2-(trifluoromethyl)benzonitrile.

Its CAS No. is 654-70-6. 

4-Amino-2-(trifluoromethyl)benzonitrile is an organic compound with the chemical formula C7H5F3N2, known for its distinct functional groups and interesting properties. It is a substituted benzonitrile with an amino group (-NH2) at position 4 of the benzene ring, a trifluoromethyl group (-CF3) at position 2, and a nitrile group (-CN) at position 1.

Our pharmaceutical intermediates can be used in a variety of APIs.



654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile Specifications


Product Category

Pharmaceutical intermediates

CAS NO

654-70-6

Product Specifications

White to off-white powder

Melting point: 141-145 °C(lit.)

Boiling point: 294.5±40.0 °C(Predicted)

Density: 1.37±0.1 g/cm3(Predicted)

Storage temp.: Keep in dark place,Sealed in dry,Room Temperature


654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile Factory display


Office Environment

654-70-6

Laboratory

Enzalutamide Pharmaceutical intermediates

Workshop/Warehouse

654-70-6


654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile Certification


Certificate

4-Amino-2-(trifluoromethyl)benzonitrile


654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile FAQ


1. Manufacturer or trading company for 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile?

4-Amino-2-(trifluoromethyl)benzonitrile is produced by EASTFINE , and we are in charge of  overseas selling . Not just trading company .


2. 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile supplier and factories or wholesale locates in such countries like?

China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.


3. Can I get a sample for trying 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile?

Yes , you can have 4-Amino-2-(trifluoromethyl)benzonitrile sample for starting the business , but it is not free


4. What the MOQ of 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile?

Please contact our sales team for more details.


5. What is 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile used for?

4-Amino-2-(trifluoromethyl)benzonitrile is commonly used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. Its unique molecular structure, especially the presence of the trifluoromethyl group, can enhance chemical reactivity and influence the properties of the compounds it is incorporated into.


6. What are the key chemical features of 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile?

· Amino group (-NH2): This group can participate in reactions like nucleophilic substitution and can form hydrogen bonds, influencing the reactivity and solubility of the compound.

· Trifluoromethyl group (-CF3): This electronegative group typically increases the hydrophobicity and stability of the molecule, making it useful in designing compounds with specific solubility and reactivity characteristics.

· Benzonitrile backbone: The nitrile group (-CN) at the end of the benzene ring gives the compound significant electronic properties, such as electron-withdrawing behavior, affecting its reactivity.


7. Is 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile toxic?

As with many organic compounds, safety considerations should be taken into account. 4-Amino-2-(trifluoromethyl)benzonitrile is not widely known to be highly toxic, but exposure should be minimized. Standard safety precautions such as wearing gloves, goggles, and working in a well-ventilated area should be followed when handling it.


8. How is 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile synthesized?

This compound can be synthesized through various methods, often involving the functionalization of benzonitrile with appropriate reagents that introduce both the amino and trifluoromethyl groups. Specific synthetic routes may involve reactions such as nucleophilic substitution or electrophilic aromatic substitution.


9. What are the applications of the trifluoromethyl group in organic synthesis?

The trifluoromethyl group significantly influences a molecule’s properties by increasing lipophilicity, stability, and metabolic resistance, making it valuable in drug discovery. It can also affect the pharmacokinetics and efficacy of pharmaceutical compounds.


10. Is 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile used in any specific industries?

Yes, it's primarily used in the pharmaceutical industry, where it serves as a precursor for synthesizing active pharmaceutical ingredients (APIs) and potentially in agrochemical production for the development of pesticides and herbicides.


11. Are there any environmental concerns with this compound?

Compounds with fluorine atoms, particularly trifluoromethyl groups, are often associated with environmental persistence, as they can be resistant to degradation. Proper disposal and handling protocols should be followed to minimize environmental impact.


12. What are the physical properties of 654-70-6 4-Amino-2-(trifluoromethyl)benzonitrile?

This compound is typically a solid at room temperature, and its melting point, solubility, and other physical properties would depend on the specific form and purity of the compound.


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