143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile

143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Introduction

We are a pharmaceutical intermediate manufacturer of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile.

Its CAS No. is 143782-23-4.

4-Isothiocyanato-2-(trifluoromethyl)benzonitrile is an organic compound that belongs to the class of substituted benzonitriles. Its chemical formula is C8H4F3N2S, and it features a nitrile group (-CN), a trifluoromethyl group (-CF3), and an isothiocyanate group (-N=C=S) attached to a benzene ring. Specifically, the trifluoromethyl group is located at position 2, the isothiocyanate group is at position 4, and the nitrile group is at position 1.

Our pharmaceutical intermediates can be used in a variety of APIs.

143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Specifications

143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Factory display

Office Environment

Laboratory

Workshop/Warehouse

143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Certification

Certificate

143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile FAQ

1. Manufacturer or trading company for 143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile?

4-isothiocyanato-2-(trifluoroMethyl)benzonitrile is produced by EASTFINE , and we are in charge of  overseas selling . Not just trading company .

2. 143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile supplier and factories or wholesale locates in such countries like?

China,America,Brazil,England,Russia,Poland,India,Pakistan,NewZealand,Korea,Australia,Dubai,Turkey,Indonesia,UAE.

3. Can I get a sample for trying 143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile?

Yes , you can have 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile sample for starting the business , but it is not free

4. What the MOQ of 143782-23-4 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile?

Please contact our sales team for more details.

5. What is 143782-23-4 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile used for?

· This compound is used primarily as an intermediate in organic synthesis. It can be involved in the preparation of pharmaceuticals, agrochemicals, and functional materials. The isothiocyanate group makes it useful in reactions like nucleophilic substitution and in the formation of thiourea derivatives.

· It may also be studied for its biological activity, as compounds with isothiocyanate groups have shown interesting anticancer and antimicrobial properties.

6. What are the chemical features of 143782-23-4 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile?

· Isothiocyanate group (-N=C=S): This group is reactive and can form covalent bonds with nucleophiles such as amines and thiols. It plays an important role in biological activities and in the synthesis of diverse chemical compounds.

· Trifluoromethyl group (-CF3): This electron-withdrawing group can influence the stability, lipophilicity, and reactivity of the molecule. It can enhance the molecule's solubility in nonpolar solvents and increase the compound's metabolic stability.

· Benzonitrile backbone (-CN): The nitrile group is an electron-withdrawing group that significantly affects the electronic properties of the molecule, making it a strong nucleophile and increasing the reactivity in specific reactions.

7. What is the significance of the isothiocyanate group?

The isothiocyanate (-N=C=S) group is notable for its reactivity. It is commonly involved in the formation of various biologically active compounds. It can react with amines to form thioureas, with alcohols to form thiocarbamates, and can also undergo cyclization reactions. The isothiocyanate group is often explored for its potential antimicrobial, anticancer, and anti-inflammatory properties.

8. How is 143782-23-4 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile synthesized?

· Synthesis of 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile typically involves introducing the isothiocyanate group to a trifluoromethyl-substituted benzonitrile. This can be achieved through a reaction with a reagent like phosgene or thiophosgene, which reacts with an amine or another nucleophile to produce the isothiocyanate functional group.

· Another potential route involves the use of specialized reactive intermediates that introduce the trifluoromethyl group and nitrile group during the synthesis.

9. Is 143782-23-4 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile toxic?

· Isothiocyanates in general can be toxic and should be handled with care. 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile may cause irritation to the skin, eyes, and respiratory system, and it is recommended to handle it in a well-ventilated area with appropriate safety measures (e.g., gloves, goggles, lab coat).

· Always refer to specific Material Safety Data Sheets (MSDS) for detailed safety instructions and toxicity data.

10. What are the applications of the trifluoromethyl group in organic chemistry?

The trifluoromethyl group is known for its ability to modulate chemical properties such as:

· Increasing the lipophilicity and hydrophobicity of molecules, which can be advantageous in drug design.

· Enhancing stability and resistance to degradation, making compounds more robust in biological systems.

· Electron-withdrawing effect, which can alter the reactivity of the attached functional groups, often leading to more selective reactions in synthesis.

11. What industries use 143782-23-4 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile?

This compound is primarily used in chemical research, pharmaceuticals, and agrochemicals:

· It may be used to synthesize novel therapeutic agents or in the development of pesticides.

· In materials science, it may be used to produce functionalized polymers or coatings with specific properties such as resistance to environmental factors.

12. Are there environmental concerns with this compound?

As with many organofluorine compounds, 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile may be persistent in the environment due to the stability imparted by the trifluoromethyl group. Proper disposal and waste management practices should be followed to minimize environmental impact, and the compound should be used in controlled environments.

13. What are the physical properties of 143782-23-4 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile?

This compound is typically a solid at room temperature, with its physical properties, including melting point, solubility, and vapor pressure, depending on its specific form and purity. It is likely to be insoluble in water but soluble in organic solvents like dichloromethane, acetone, or ethanol.

14. How stable is 143782-23-4 4-Isothiocyanato-2-(trifluoromethyl)benzonitrile?

The compound is generally stable under normal conditions; however, the reactivity of the isothiocyanate group means that it should be stored away from moisture and nucleophilic reagents that could react with it. Like many isothiocyanates, it may degrade under extreme conditions such as high temperature or exposure to strong acids or bases.