Enzalutamide
112704-79-7
White Solid
Melting point: 211-215 °C (lit.)
Boiling point: 289.4±25.0 °C(Predicted)
Density: 1.7218 (rough estimate)
Storage temp.: Sealed in dry,Room Temperature
Availability: | |
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Product Description
Product Category | Enzalutamide |
CAS NO | 112704-79-7 |
Product Specifications | White Solid Melting point: 211-215 °C (lit.) Boiling point: 289.4±25.0 °C(Predicted) Density: 1.7218 (rough estimate) Storage temp.: Sealed in dry,Room Temperature |
112704-79-7 4-BROMO-2-FLUOROBENZOIC ACID.pdf
4-Bromo-2-fluorobenzoic acid is produced by EASTFINE , and we are in charge of overseas selling . Not just trading company.
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4-Bromo-2-fluorobenzoic acid is an organic compound with the chemical formula C7H4BrFO2. It consists of a benzoic acid (aromatic carboxyl group) with a bromine atom at the para position (4) and a fluorine atom at the meta position (2) relative to the carboxyl group.
· Carboxyl group (-COOH): Provides acidic properties and allows the compound to participate in various reactions, such as esterification and amidation.
· Bromine (Br) and Fluorine (F) atoms: Both are electron-withdrawing halogens. Bromine at the para position influences the molecule’s reactivity in substitution reactions, while fluorine at the meta position also affects electron density on the benzene ring, contributing to the compound’s overall chemical properties.
· Organic Synthesis: It is used as an intermediate in the synthesis of more complex organic compounds.
· Pharmaceutical Industry: The compound can be involved in the synthesis of bioactive molecules with potential antibacterial, anticancer, and anti-inflammatory properties.
· Agrochemical Production: It can be used as a building block for the creation of pesticides and herbicides.
· Materials Science: Used in the development of functionalized materials, including polymers and coatings.
4-Bromo-2-fluorobenzoic acid can be synthesized through several synthetic routes, including:
· Halogenation reactions: The introduction of bromine and fluorine atoms into the benzoic acid ring via electrophilic aromatic substitution.
· Starting materials: It may be synthesized from simpler benzoic acid derivatives or through direct halogenation of a benzoic acid precursor with specific reagents like bromine and fluorine.
· The use of fluorinating agents and brominating agents such as Br2 or NBS (N-Bromosuccinimide) in the presence of appropriate solvents and conditions.
· Appearance: Typically, it is a solid at room temperature, usually white to off-white in color.
· Melting Point: Around 168-172°C.
· Solubility: This compound is likely insoluble in water but soluble in organic solvents like acetone, ethanol, methanol, and dichloromethane.
· Odor: Generally, it has a faint odor, characteristic of aromatic compounds.
· Like many organic chemicals, 4-Bromo-2-fluorobenzoic acid should be handled with caution. Bromine and fluorine-containing compounds can be irritating to the skin, eyes, and respiratory system.
· Safety precautions should be taken when handling this compound, including wearing gloves, goggles, and working in a well-ventilated area.
· Always consult the Material Safety Data Sheet (MSDS) for more detailed safety information.
· The compound is of interest in drug design and medicinal chemistry due to the electron-withdrawing effects of the bromine and fluorine atoms, which can affect the reactivity and bioactivity of the compound.
· It may serve as an intermediate for the development of pharmaceuticals with antibacterial, anticancer, and anti-inflammatory properties, as many halogenated benzoic acids show promising biological activity.
· Compounds with halogens (like bromine and fluorine) can be persistent in the environment due to their chemical stability.
· While 4-Bromo-2-fluorobenzoic acid is not typically classified as highly hazardous to the environment, it should still be handled and disposed of according to environmental safety standards.
· It is advisable to follow proper disposal guidelines to avoid contamination of water and soil.
· The para-position bromine and meta-position fluorine have specific effects on the electron density of the aromatic ring. Bromine, being large and electron-withdrawing, makes the molecule more reactive in electrophilic aromatic substitution reactions, while fluorine at the meta position further influences the molecule’s overall electrophilic character and stability.
· This unique combination of halogens allows for selective nucleophilic and electrophilic substitutions, making the compound useful in synthetic chemistry.
· When stored in a cool, dry place away from direct sunlight and moisture, 4-Bromo-2-fluorobenzoic acid should remain stable for extended periods. Proper storage conditions are essential to maintain the integrity of the compound.
· Like many organic chemicals, it should be kept in tightly sealed containers to avoid contamination or degradation.