Views: 0 Author: Site Editor Publish Time: 2025-07-03 Origin: Site
4-tert-Butylphenol (CAS No. 98-53-3), also known as p-tert-butylphenol, is a versatile aromatic compound widely used as an agrochemical intermediate. It features a phenolic hydroxyl group and a bulky tert-butyl substituent that together provide chemical stability, lipophilicity, and resistance to oxidative degradation. These properties make it especially valuable in the synthesis of selective herbicides, fungicides, and industrial biocides.
This compound is often involved in the production of phenoxy herbicides and aryl ether-based actives, which are key in controlling broadleaf weeds, mildew, rust, and other threats in cereal, fruit, and industrial crops.
Acts as a starting material for the synthesis of aryl ether herbicides and fungicidal compounds with high binding affinity to plant enzyme systems.
The bulky tert-butyl group enhances fat solubility, allowing better systemic absorption and longevity in field conditions.
Compounds derived from 4-tert-butylphenol show higher resistance to UV degradation and oxidation, making them suitable for long-lasting formulations.
Plays a role in synthesis of intermediates for both soil-applied and foliar agrochemicals, providing flexibility in application timing.
Also used in resins, coatings, and stabilizers, making it a high-volume intermediate with globally optimized manufacturing standards.
Location: Ludwigshafen, Germany
Overview: BASF is a global leader in producing alkylphenol derivatives like 4-tert-butylphenol, supporting both agrochemical synthesis and industrial resins.
Specialty: Integrated production of aromatic intermediates under EU REACH guidelines.
Location: Schenectady, New York, USA
Overview: SI Group specializes in phenolic intermediates and antioxidants. Their production of 4-tert-butylphenol supports agrochemical, polymer, and lubricant industries.
Specialty: High-purity phenol chemistry and global export capabilities.
Location: Changzhou City, Jiangsu Province, China
Overview: Eastfine manufactures agrochemical intermediates including CAS 98-53-3 for use in herbicides and fungicides. Their operations emphasize international compliance, quality control, and cost-effective global supply.
Specialty: Halogenated and phenolic intermediates for agro applications.
Location: Tokyo, Japan
Overview: DIC produces a broad portfolio of specialty chemicals including phenolic compounds. Their 4-tert-butylphenol is used in synthesis of fungicides and industrial crop coatings.
Specialty: Fine chemicals with tight purity specifications.
Location: Cologne, Germany
Overview: LANXESS manufactures alkylphenols and antioxidant intermediates used in pesticides and high-performance resins. Their facilities are equipped for high-volume, low-impurity production.
Specialty: Scale manufacturing with a strong ESG focus.
Location: Chennai, India
Overview: Tagros exports key agrochemical intermediates, including 4-tert-butylphenol, for downstream herbicide and fungicide manufacturing.
Specialty: Export-grade crop protection intermediates at scale.
Location: Norderstedt, Germany
Overview: Specializing in biocidal and antifungal chemistry, Schülke produces 4-tert-butylphenol for use in agricultural disinfectants and protection products.
Specialty: Antimicrobial intermediates with regulatory compliance.
Location: Tokyo, Japan
Overview: ADEKA develops intermediates used in agrochemical synthesis and protective coatings for seeds and leaves. Their 4-tert-butylphenol serves both pesticide and plant health sectors.
Specialty: Co-formulants and stabilizers for agro applications.
Location: Manerbio, Italy
Overview: Finchimica supports European agrochemical producers with REACH-compliant intermediates like CAS 98-53-3.
Specialty: Custom synthesis and process development for aromatic intermediates.
Location: Charlotte, North Carolina, USA
Overview: Though better known for bromine and lithium products, Albemarle also produces specialty phenolic compounds used in agrochemical and resin synthesis.
Specialty: Functional intermediates for high-end chemical sectors.
Intermediates like CAS 98-53-3 support the shift toward systemic, long-residual herbicides that are rainfast and efficient at low doses.
There is growing demand for intermediates with clean degradation profiles and low toxicity, making high-purity 4-tert-butylphenol essential.
Compounds derived from this intermediate are used not just in actives but also as stabilizers or UV protectants in formulations.
With the rise of seed treatments and controlled-release fertilizers, demand for phenolic intermediates in coating agents is also expanding.
Companies are partnering with global CDMOs to ensure a secure, cost-effective supply of this and related intermediates, especially in Latin America and Southeast Asia.
CAS No. 98-53-3 (4-tert-Butylphenol) remains a cornerstone intermediate in the synthesis of modern herbicides, fungicides, and formulation aids. With manufacturers like BASF, SI Group, and Eastfine leading the charge in high-quality, scalable production, this compound continues to be vital to the evolving agrochemical landscape.
As agriculture trends toward more effective and longer-lasting protection products, intermediates like this one will only grow in strategic importance across the crop protection industry.
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