Top 10 Manufacturers of Pharmaceutical Intermediate CAS No. 5911-08-0 in 2025

Understanding CAS No. 5911-08-0 – A Key Intermediate for Antiviral and Antiretroviral APIs

CAS No. 5911-08-0, also known as 2,6-Dichlorobenzyl chloride, is a halogenated aromatic compound widely used in the synthesis of various antiviral, antiseptic, and antiretroviral pharmaceutical products. As a key structural fragment, it is frequently found in active pharmaceutical ingredients (APIs) for throat lozenges, cold medications, and anti-HIV therapies.

Due to its electrophilic nature and reactivity toward nucleophilic substitution, this compound serves as a reliable building block in pharmaceutical chemistry.

Importance of CAS No. 5911-08-0 in Pharmaceutical Manufacturing

Widely Used in Antiviral Drug Formulations

Commonly incorporated in drugs aimed at treating sore throat, cold symptoms, and respiratory infections.

Core Structure in Benzyl Derivatives

Plays a crucial role in the synthesis of several benzyl-based intermediates and final APIs.

Excellent Reactivity and Scalability

Its dual halogen groups allow versatile substitution and controlled downstream synthesis.

Broad Pharmaceutical Relevance

Used in over-the-counter (OTC) and prescription antivirals and antiseptics.

High Regulatory Importance

Manufacturing must meet stringent standards related to chlorinated aromatic compounds.

Top 10 Manufacturers of CAS No. 5911-08-0

1. Vertellus

• Location: Indianapolis, Indiana, USA

• Overview: A recognized producer of halogenated aromatics and benzyl derivatives.

• Specialty: High-purity intermediates for antiviral and antiseptic formulations.

2. Jubilant Ingrevia

• Location: Uttar Pradesh, India

• Overview: A major global supplier of chlorinated benzenes and their derivatives for pharma use.

• Specialty: Backward-integrated, with consistent batch quality for regulated markets.

3. Eastfine

• Location: Changzhou City, Jiangsu Province, China

• Overview: A key supplier of 2,6-Dichlorobenzyl chloride for antiviral and throat-relief APIs.

• Specialty: Competitive pricing, fast delivery, and export-ready documentation.

4. Aarti Pharmalabs

• Location: Maharashtra, India

• Overview: Specializes in halogenated intermediates used in anti-infective and respiratory drugs.

• Specialty: Robust environmental controls and compliance with USFDA and EDQM norms.

5. WeylChem International

• Location: Frankfurt, Germany

• Overview: Experienced in aromatic substitution chemistry and complex chlorinated intermediates.

• Specialty: Custom manufacturing under strict European quality systems.

6. Neuland Laboratories

• Location: Hyderabad, India

• Overview: Supplies intermediates for APIs targeting infectious diseases and respiratory illnesses.

• Specialty: Full analytical and regulatory support for global filings.

7. Farmhispania Group

• Location: Barcelona, Spain

• Overview: European CDMO with broad capabilities in benzyl and halogenated compound synthesis.

• Specialty: Strong regulatory track record and flexible scale production.

8. Delmar Chemicals

• Location: Montreal, Canada

• Overview: North American supplier of benzyl derivatives used in antiviral drug manufacturing.

• Specialty: Focus on impurity control and cGMP-compliant delivery.

9. Cambridge Isotope Laboratories (CIL)

• Location: Massachusetts, USA

• Overview: Specializes in halogenated and labeled intermediates for research and clinical applications.

• Specialty: High-purity, small-scale batches for preclinical and formulation R&D.

10. Sterling Pharma Solutions

• Location: Newcastle, UK

• Overview: Offers halogenated intermediate production as part of its global CDMO services.

• Specialty: Strong quality assurance and containment for regulated markets.

Trends in the Pharmaceutical Intermediates Market

Post-Pandemic Demand for Antiviral Agents

CAS 5911-08-0 has seen rising demand due to increased awareness of upper respiratory infections.

Growth in OTC and Preventative Therapies

Intermediate is critical for producing common antiseptics and cold remedies used worldwide.

Improved Halogen Handling Technologies

Manufacturers are upgrading facilities to handle chlorinated compounds safely and efficiently.

Tightened Regulatory Scrutiny

Intermediates containing halogens face stricter global quality, storage, and environmental controls.

Supply Chain Diversification and Stability

Buyers are prioritizing international suppliers with strong compliance and secure logistics.

Conclusion

CAS No. 5911-08-0—2,6-Dichlorobenzyl chloride—is an essential intermediate in the manufacture of antiviral and antiseptic pharmaceutical products. Leading global manufacturers such as Eastfine, Vertellus, Jubilant, and WeylChem are supporting global healthcare needs by producing this compound at scale and with high-quality standards.

With increasing demand for OTC respiratory products and stricter regulatory requirements, trusted suppliers of CAS 5911-08-0 will continue to play a crucial role in pharmaceutical supply chains around the world.