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2-Methyl-1-Methylthio-2-Propylamine: Your Guide to a Key Agrochemical Intermediate

Views: 0     Author: Site Editor     Publish Time: 2025-05-27      Origin: Site

Introduction

In the world of agrochemical intermediates, 2-Methyl-1-methylthio-2-propylamine, identified as CAS 36567-04-1, is a cornerstone compound driving the synthesis of modern pesticides and fungicides. At EASTFINE, a leading B2B intermediates manufacturer with over 30 years of experience exporting high-quality chemicals to global markets, we recognize the critical role this compound plays in crop protection. This comprehensive guide explores the chemistry, applications, production processes, regulatory framework, market dynamics, and future potential of 2-Methyl-1-methylthio-2-propylamine, offering valuable insights for agrochemical manufacturers seeking reliable intermediates.

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Unveiling the Chemistry of 2-Methyl-1-Methylthio-2-Propylamine

2-Methyl-1-methylthio-2-propylamine is an organic compound with a sulfur-containing structure, making it a vital building block in agrochemical synthesis. Its unique properties enable it to serve as a key intermediate in the production of crop protection chemicals.

Chemical Structure and Properties

This compound, with the molecular formula C5H13NS and a molecular weight of 119.23 g/mol, features a propylamine backbone substituted with a methylthio (-SCH3) group on the first carbon and two methyl groups on the second carbon. The sulfur atom enhances its reactivity, making it ideal for forming thioether linkages critical in agrochemical molecules.

It appears as a colorless to light yellow liquid with a characteristic sulfurous odor, typical of thioethers. Its boiling point ranges from 140-150°C, and it is soluble in organic solvents like ethanol, dichloromethane, and toluene, with limited water solubility. With a density of approximately 0.90 g/cm³, it is well-suited for industrial reaction conditions.

Role in Agrochemical Synthesis

In agrochemical manufacturing, intermediates like 2-Methyl-1-methylthio-2-propylamine are essential for constructing complex molecules used in pesticides, herbicides, and fungicides. The methylthio and amine groups enable reactions that form sulfur- or nitrogen-containing structures, which are prevalent in crop protection products. EASTFINE’s expertise ensures reliable production for B2B clients in the agricultural sector.

Applications of CAS 36567-04-1 in Crop Protection

The primary application of 2-Methyl-1-methylthio-2-propylamine lies in synthesizing agrochemical active ingredients, particularly for pesticides and fungicides that safeguard crops and boost agricultural yields.

Synthesis of Pesticides and Fungicides

This intermediate is integral to producing sulfur-containing agrochemicals, such as thiophene-based pesticides or thioether-linked fungicides. These compounds combat pests and pathogens threatening crops like rice, wheat, and soybeans. The methylthio group enables the formation of stable, bioactive molecules that resist environmental degradation, ensuring long-lasting crop protection.

Use in Insecticides

2-Methyl-1-methylthio-2-propylamine is valuable in synthesizing insecticides targeting pests like aphids, beetles, or locusts. It serves as a precursor for thioether-based compounds that disrupt pest metabolism or nervous systems, critical for high-demand agricultural markets like India and Brazil.

Role in Fungicides

Fungicides derived from this compound protect crops from diseases like powdery mildew, rust, or blight. The sulfur functionality enhances the efficacy of fungicidal molecules, making it a key component in products for vineyards, orchards, and grain fields.

Broader Agrochemical Applications

Beyond pesticides and fungicides, 2-Methyl-1-methylthio-2-propylamine supports the synthesis of specialty agrochemicals, such as plant growth regulators or soil conditioners. Its versatility enables formulations that address emerging challenges, like climate-resilient crops or sustainable farming practices.

Custom Synthesis Opportunities

For agrochemical companies engaged in R&D, this intermediate offers flexibility for developing tailored active ingredients. Its reactive sulfur and amine groups allow chemists to modify its structure for novel applications, such as herbicides targeting resistant weeds. EASTFINE’s R&D capabilities support these innovative needs.

Producing 2-Methyl-1-Methylthio-2-Propylamine with Precision

Manufacturing 2-Methyl-1-methylthio-2-propylamine requires expertise and advanced infrastructure, qualities EASTFINE has perfected over 30 years as a trusted intermediates supplier.

Synthesis Pathway

The production of this compound involves a multi-step process:

  1. Amine Formation: Starting with a propylamine derivative, such as 2-methyl-2-propylamine (tert-butylamine), the amine backbone is established.

  2. Thioether Introduction: The methylthio group is introduced using sulfur-containing reagents like methyl mercaptan or dimethyl disulfide under basic conditions.

  3. Purification: The crude product undergoes vacuum distillation or column chromatography to achieve agrochemical-grade purity, typically ≥98%.

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Reaction Conditions

Synthesis demands controlled conditions, including temperatures of 40-80°C and an inert atmosphere (e.g., nitrogen) to prevent sulfur oxidation. Catalysts like sodium hydroxide or phase-transfer catalysts enhance reaction efficiency and yield.

Industrial Equipment

EASTFINE’s state-of-the-art facilities feature stainless steel reactors, vacuum distillation units, and high-pressure systems to produce 2-Methyl-1-methylthio-2-propylamine at scale. Analytical tools like High-Performance Liquid Chromatography (HPLC) and Gas Chromatography-Mass Spectrometry (GC-MS) ensure consistent quality for agrochemical applications.

Production Challenges

Key challenges include managing the volatility of sulfur reagents and preventing side reactions, such as disulfide formation or amine degradation. EASTFINE’s rigorous quality control, refined over decades, optimizes reaction parameters and employs advanced purification techniques.

Quality Standards

Agrochemical-grade 2-Methyl-1-methylthio-2-propylamine requires high purity to ensure efficacy and safety in downstream products. EASTFINE provides Certificates of Analysis (CoA) with each batch, detailing purity, residual solvents, and impurity profiles.

Navigating Regulatory and Safety Requirements

Exporting CAS 36567-04-1 for agrochemical use demands compliance with international regulations and robust safety protocols, reflecting its critical role in crop protection.

Global Regulatory Compliance

Agrochemical intermediates must meet standards set by organizations like the Food and Agriculture Organization (FAO) and national bodies such as the U.S. EPA or EU’s EFSA. EASTFINE ensures adherence to Good Manufacturing Practices (GMP) and provides comprehensive documentation, including Safety Data Sheets (SDS) and CoAs, to support clients in regulated markets.

Export Documentation

Exports require compliance with the Harmonized System (HS) code 2930.90 (organo-sulfur compounds). EASTFINE includes detailed documentation with each shipment, ensuring seamless customs clearance in markets like India, Brazil, and the U.S. UN-compliant packaging is standard for hazardous materials.

Safety Profile

2-Methyl-1-methylthio-2-propylamine is flammable (flash point ~50°C) and may cause skin or respiratory irritation due to its amine and sulfur components. EASTFINE’s facilities are equipped with explosion-proof systems, proper ventilation, and trained personnel to handle these risks safely.

Environmental Responsibility

Sulfur-containing waste from synthesis must comply with regulations like REACH (Europe) or TSCA (U.S.). EASTFINE adopts green chemistry practices, such as solvent recycling and waste neutralization, to minimize environmental impact, aligning with global sustainability goals.

Market Dynamics for 2-Methyl-1-Methylthio-2-Propylamine

As a B2B exporter, EASTFINE leverages its deep understanding of the global agrochemical intermediates market to deliver this compound to clients worldwide.

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Demand Drivers

The demand for 2-Methyl-1-methylthio-2-propylamine is driven by the global need for effective crop protection solutions. Rising agricultural output in regions like Asia and Latin America fuels demand for pesticides and fungicides. The push for sustainable, high-efficacy agrochemicals further boosts the need for specialized intermediates.

Regional Opportunities

India, a major agricultural hub, is a key importer due to its vast crop production. Brazil, with expansive soybean and sugarcane fields, is another high-demand market. The U.S., Australia, and Mexico offer growth opportunities as farmers adopt advanced pest control solutions, aligning with EASTFINE’s export markets.

Competitive Landscape

While China dominates intermediates production with cost advantages, EASTFINE differentiates itself through quality, reliability, and GMP-certified processes. Our 30 years of experience enable us to compete in premium markets, delivering agrochemical-grade intermediates to discerning clients.

Logistics and Shipping

As a flammable liquid, CAS 36567-04-1 requires transport under Dangerous Goods regulations (e.g., IATA Class 3). EASTFINE uses temperature-controlled containers to ensure stability during exports, critical for clients in distant markets like Australia or Mexico.

Why Choose EASTFINE for Your Agrochemical Needs?

With over 30 years of experience as a B2B agrochemical intermediates manufacturer, EASTFINE is your trusted partner for sourcing 2-Methyl-1-methylthio-2-propylamine. Our expertise, global reach, and commitment to quality set us apart.

Unmatched Expertise

EASTFINE’s three decades of experience in fine chemicals ensure mastery in producing complex intermediates like 2-Methyl-1-methylthio-2-propylamine. Our skilled chemists optimize synthesis processes to deliver high-purity products tailored to agrochemical needs.

Scalability and Customization

From R&D batches to metric-ton commercial orders, EASTFINE adapts to your requirements. Our 24/7 R&D team supports custom synthesis, enabling innovative agrochemical formulations for pest or disease resistance.

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Global Export Excellence

Serving over 20 countries, EASTFINE’s robust logistics network ensures timely delivery. Our expertise in international regulations, from HS codes to environmental compliance, guarantees seamless exports to markets like India, Brazil, and the U.S.

Quality Assurance

Our GMP-certified facilities and 360-degree quality control deliver agrochemical-grade intermediates (≥98% purity). Detailed CoAs and full traceability ensure confidence in every batch.

The Future of CAS 36567-04-1 in Agrochemicals

The outlook for 2-Methyl-1-methylthio-2-propylamine is promising, driven by innovation and the global demand for sustainable agriculture.

Sustainability in Production

EASTFINE is adopting green chemistry practices, such as bio-based reagents and energy-efficient processes, to reduce the environmental footprint of this compound’s production, meeting client demands for sustainability.

Technological Advancements

Automation and AI-driven optimization enhance EASTFINE’s production efficiency. Continuous flow reactors could streamline synthesis, lowering costs and improving yields for 2-Methyl-1-methylthio-2-propylamine.

Expanding Agrochemical Applications

Research into sulfur-containing agrochemicals may uncover new uses for this intermediate, such as in next-generation herbicides or biopesticides. EASTFINE’s R&D capabilities position us to support these advancements.

Resilient Supply Chains

Post-pandemic, supply chain reliability is critical. EASTFINE’s diversified sourcing and robust logistics ensure uninterrupted supply of CAS 36567-04-1, even in challenging times.

Conclusion

2-Methyl-1-methylthio-2-propylamine, or CAS 36567-04-1, is a cornerstone of agrochemical innovation, enabling the synthesis of pesticides and fungicides that protect global crops. At EASTFINE, with over 30 years of experience as a B2B intermediates factory, we deliver this compound with unmatched quality and global reliability. Whether you’re developing advanced crop protection solutions or scaling up production, EASTFINE is your trusted partner, driving success in the agricultural industry.


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